Mis amigas me apoyan, y eso hace que no me rinda tan rápido y que me esfuerce más.

Amigas is the feminine plural form of amigo/amiga, so it means female friends.

• mis amigas = my female friends
• mis amigos = my male friends or my friends if the group is mixed

So this sentence specifically tells you that the speaker’s friends are female.

Apoyan comes from apoyar, which often means to support.

So:

• me apoyan = they support me

The pronoun me means me and is the object of the verb. Spanish often uses object pronouns before the verb:

• me apoyan = they support me
• te apoyan = they support you
• nos apoyan = they support us

Here, mis amigas is the subject, and me is the person receiving the support.

Eso hace que literally means that makes it so that... or more naturally that makes... / that causes...

In this sentence:

• Mis amigas me apoyan = My friends support me
• y eso hace que... = and that makes it so that... / and that causes...

This structure is very common in Spanish when one thing causes an effect.

Because after hace que, Spanish normally uses the subjunctive.

So:

• hace que no me rinda
• hace que me esfuerce más

The subjunctive is used here because the second part is presented as the result/effect of the first part, triggered by hace que.

Compare:

• Me rindo = I give up
• Me esfuerzo = I make an effort / I try hard

But after hace que:

• me rinda
• me esfuerce

Those are present subjunctive forms.

They come from these verbs:

• rinda ← rendirse = to give up / surrender
• esfuerce ← esforzarse = to make an effort / strive / try hard

Both are reflexive verbs, which is why you see me with them:

• me rindo = I give up
• me esfuerzo = I make an effort

In the subjunctive:

• me rinda
• me esfuerce

Because both verbs are reflexive, and each verb needs its own reflexive pronoun.

So Spanish says:

• no me rinda
• me esfuerce más

You cannot normally use just one me for both and let it cover everything automatically. Each reflexive verb keeps its own pronoun.

That is why the sentence does not say something like:

• no me rinda tan rápido y esfuerce más ✘

Instead, it repeats the pronoun:

• no me rinda tan rápido y que me esfuerce más ✔

The first que is required after hace que.

The second que is repeated to make the structure clearer and more balanced:

• hace que no me rinda tan rápido y que me esfuerce más

This repetition is very natural in Spanish when linking two subordinate ideas. It helps show that both actions depend on hace que.

You may sometimes hear or see the second que omitted in other contexts, but here repeating it sounds very natural and clear.

Here rendirse means to give up.

Although it can also mean to surrender, in everyday speech it often means stopping because something is difficult.

So:

• no me rinda tan rápido = I don’t give up so quickly

In natural English, you might translate it as:

• I don’t give up as quickly
• I don’t give up so easily/so fast

depending on context.

Tan means so and rápido means quickly/fast.

So literally:

• tan rápido = so quickly

In this sentence, with the negative:

• no me rinda tan rápido

the idea is:

• I don’t give up so quickly
• I don’t give up as quickly

Spanish often uses tan + adjective/adverb in this kind of structure, where English may choose so, as, or just a smoother natural phrasing.

Más means more.

• me esfuerzo = I make an effort / I try hard
• me esfuerzo más = I make more effort / I try harder

So the second result is:

• that I put in more effort
• that I try harder

This pairs nicely with the first part:

• not give up so quickly
• try harder

Yes. English does not usually say to effort oneself, but Spanish commonly uses the reflexive verb esforzarse.

Some natural translations are:

• to make an effort
• to try hard
• to push oneself
• to work harder

So que me esfuerce más could be translated in several natural ways depending on context:

• that I make more of an effort
• that I try harder
• that I work harder

The present tense here describes a general or current reality:

• Mis amigas me apoyan = My friends support me
• eso hace que... = that makes...

It is not talking about one single completed event, but about an ongoing situation or a usual effect.

So the sentence means something like:

• My friends support me, and that makes me not give up so quickly and try harder.

Not with the same meaning.

• hacer que + subjunctive = to cause/make someone do something
• hacer algo para que + subjunctive = to do something so that...

Here the sentence means their support causes this effect, so hace que is the right structure.

If you used para que, the meaning would change to something more like in order that or so that, which is not what this sentence is doing.

Yes, this is the normal order.

• no goes before the pronoun and verb phrase
• me comes before the conjugated verb
• rinda is the verb
• tan rápido adds the idea of so quickly

So:

• no me rinda tan rápido

is the natural order for that I not give up so quickly.

Yes. That is exactly what eso is doing here.

In:

• Mis amigas me apoyan, y eso hace que...

eso refers to the whole fact that my friends support me.

So eso = that
meaning that fact, that situation, or that support.

It breaks down like this:

1. Mis amigas me apoyan
   = main idea

2. y eso hace que...
   = introduces the consequence

3. no me rinda tan rápido
   = first result

4. y que me esfuerce más
   = second result

So the full pattern is:

• [Cause] + y eso hace que + [subjunctive result 1] + y que + [subjunctive result 2]

This is a very useful pattern in Spanish for expressing cause and effect.