Learn Italian: Mi piace questo stile di vita, nonostante la differenza culturale. - I like this lifestyle, despite the cultural difference.

Nonostante (despite/although) is famous for requiring the subjunctive, but only if it introduces a clause with a verb. In this sentence, it functions as a preposition followed simply by a noun phrase (la differenza culturale). Because there is no verb attached to the "despite" part of the sentence, the subjunctive isn't needed!

Why is it questo stile? Aren't words ending in "-e" usually feminine?

Nouns ending in -e in Italian can actually be either masculine or feminine, and you generally just have to memorize them. Stile (style) happens to be masculine. Paying attention to the word immediately before it—like the masculine demonstrative adjective questo—is a great trick to help you remember its gender.

How does Italian form compound words like "lifestyle"?

Unlike English, which easily mashes two nouns together to make words like "lifestyle" or "teacup", Italian typically links the two nouns with the preposition di (of). Therefore, "lifestyle" is expressed literally as "style of life" (stile di vita).

As a quick refresher, why do we use the singular piace instead of piacciono here?