Mi hermana quiere un trabajo permanente en una empresa de tecnología.

In modern Spanish, possessives like mi, tu, su, nuestro usually go directly before the noun without an article:

• mi hermana = my sister
• tu coche = your car

Using an article before mi here would sound wrong in standard modern Spanish.

Spanish often leaves out subject pronouns because the verb ending already shows who is doing the action.

• quiere = he/she/it wants

So Mi hermana quiere... already clearly means My sister wants...
You could say Ella quiere..., but it is usually unnecessary unless you want emphasis or contrast.

Quiere is the third-person singular form of the verb querer.

Here it matches mi hermana, which is she:

• yo quiero = I want
• tú quieres = you want
• él/ella quiere = he/she wants

So Mi hermana quiere means My sister wants.

Spanish often uses the indefinite article where English also uses a/an:

• un trabajo = a job
• una empresa = a company

They are different nouns, so each one needs its own article. Also, the articles must match the gender of the noun:

• trabajo is masculine → un trabajo
• empresa is feminine → una empresa

In Spanish, every noun has grammatical gender.

• trabajo is masculine, so it takes un / el
• empresa is feminine, so it takes una / la

There is not always a perfect rule, but word endings often help:

• many nouns ending in -o are masculine: trabajo
• many nouns ending in -a are feminine: empresa

You still need to learn each noun with its article whenever possible.

In Spanish, adjectives usually come after the noun:

• un trabajo permanente = a permanent job
• una casa grande = a big house

So trabajo permanente is the normal order.
Putting the adjective before the noun is sometimes possible in Spanish, but it usually changes the tone, emphasis, or sounds literary. Here, the normal choice is un trabajo permanente.

Permanente means permanent.

So un trabajo permanente is understandable and correct. However, in Spain, when talking about employment, people very often say:

• un trabajo fijo
• un contrato indefinido

These can sound more natural in everyday job-related contexts. Still, trabajo permanente is perfectly understandable and grammatically correct.

Spanish often uses de + noun to describe what something is related to.

• una empresa de tecnología = a technology company literally: a company of technology

This structure is very common. Another possible version is:

• una empresa tecnológica

Both are correct.
Empresa de tecnología focuses on the field or sector.
Empresa tecnológica uses an adjective and is also very natural.

Because querer does not require a preposition before a direct object.

• quiere un trabajo = wants a job

The personal a in Spanish is used mainly before specific people:

• Veo a mi hermana = I see my sister

But un trabajo is a thing, not a person, so there is no a.

The accent mark shows where the stress goes:

• tec-no-lo-GÍ-a

Without the accent, Spanish stress rules would suggest a different pronunciation. The written accent helps show the correct stressed syllable.

It is also useful because tecnología has a hiatus at the end: -gí-a, pronounced in separate syllables.

In quiere, the qu spelling represents a k sound before e or i.

So:

• quiere is pronounced roughly like KYEH-reh

The u in que and qui is normally silent in Spanish:

• que sounds like keh
• qui sounds like kee

That is why quiere does not sound like kwee-ere.

The given order is the most neutral and natural:

• Mi hermana quiere un trabajo permanente en una empresa de tecnología.

Spanish word order is somewhat flexible, but changes usually add emphasis or sound less neutral. For example:

• En una empresa de tecnología, mi hermana quiere un trabajo permanente.

This is still grammatical, but it emphasizes where she wants the job.

So the original sentence is the best basic version for most situations.