Il trasloco di Sara è domani mattina.

Trasloco means a move, especially moving house / moving to a new home.

So Il trasloco di Sara means Sara’s move or Sara’s house move.

It is a noun, not a verb.
If you wanted the verb to move house, Italian would usually use traslocare.

• Sara trasloca domani mattina = Sara is moving tomorrow morning
• Il trasloco di Sara è domani mattina = Sara’s move is tomorrow morning

Because trasloco is a singular masculine noun, so it normally takes the definite article il when you mean the move.

• il trasloco = the move

In this sentence, the speaker is referring to a specific move: Sara’s move.

Italian uses articles more often than English does, so il sounds completely normal here.

Di Sara means of Sara / Sara’s, and it clearly identifies whose move it is.

Italian often prefers article + noun + di + person:

• il trasloco di Sara
• la macchina di Luca
• il libro di Marta

You could say il suo trasloco, but suo can be ambiguous, because it could mean his, her, its, or even their depending on context.
So di Sara is clearer.

Yes, literally it is of Sara, but in natural English we usually translate it as Sara’s.

So:

• il trasloco di Sara = literally the move of Sara
• natural English: Sara’s move

This is a very common Italian structure.

This is a very common feature of Italian.

Italian often uses the present tense to talk about the future, especially when the event is:

• scheduled
• planned
• certain
• already arranged

So è domani mattina is natural and means something like is tomorrow morning.

English does something similar in sentences like:

• The meeting is tomorrow
• My flight is at 8

Italian can also use the future:

• Il trasloco di Sara sarà domani mattina

That is grammatical too, but è domani mattina is very natural in everyday speech.

Yes, absolutely.

Both are correct:

• Il trasloco di Sara è domani mattina
• Il trasloco di Sara sarà domani mattina

The version with è often sounds more immediate and conversational, especially for something already arranged.
The version with sarà is a bit more explicitly future, and may sound slightly more formal or deliberate depending on context.

Because many Italian time expressions do not need a preposition.

So you simply say:

• domani = tomorrow
• domani mattina = tomorrow morning
• stasera = tonight
• lunedì = on Monday

That is different from English, which often uses words like on, at, or in.

Examples:

• Parto domani. = I’m leaving tomorrow.
• Ci vediamo lunedì. = We’ll see each other on Monday.
• Il trasloco è domani mattina. = The move is tomorrow morning.

You should think of it as a normal time expression made of two words:

• domani = tomorrow
• mattina = morning

Together, domani mattina means tomorrow morning.

Italian commonly builds time expressions this way:

• domani sera = tomorrow evening
• domani pomeriggio = tomorrow afternoon
• domani mattina = tomorrow morning

Because this sentence is structured like:

• subject: Il trasloco di Sara
• verb: è
• time expression: domani mattina

So it works like Sara’s move is tomorrow morning.

This is a very natural way to give information about when something happens.

Italian word order is flexible, so other orders are possible for emphasis, such as:

• Domani mattina è il trasloco di Sara

But the original order is neutral and straightforward.

Yes, and that is also very natural.

The difference is mostly in focus:

• Il trasloco di Sara è domani mattina focuses on the move as an event.
• Sara trasloca domani mattina focuses on Sara and the action of moving.

Both are correct, but they are built differently:

• trasloco = noun, move
• trasloca = verb, moves / is moving house

Because nouns in Italian have grammatical gender, and trasloco happens to be masculine.

So you say:

• il trasloco
• un trasloco

There is not always a logical reason that helps an English speaker predict gender; it is often something you learn together with the noun.

A good habit is to learn nouns with their article:

• il trasloco
• la casa
• il problema
• la macchina

It is understandable, but in natural English people often prefer slightly different wording, such as:

• Sara is moving tomorrow morning
• Sara’s move is tomorrow morning
• Sara’s moving day is tomorrow morning (depending on context)

The Italian sentence itself is perfectly natural.
The exact best English translation depends on how literal or natural you want to be.

Usually trasloco refers to moving from one home or premises to another, including the whole process of changing residence and moving your belongings.

So it is more specific than just moving one object from place to place.

For example:

• Fare un trasloco = to do a house move / to move house
• Ditta di traslochi = moving company

So in this sentence, trasloco clearly means that Sara is changing home or location, not just moving a box.

It is pronounced roughly trah-ZLOH-koh.

A few useful points:

• the stress is on lo: traslòco
• tr is pronounced clearly
• the final -co sounds like koh, not like English co in every context

If you say it with clear Italian vowels, you will sound much more natural: tra-sLO-co.

It is neutral and natural.
You could use it in everyday conversation without any problem.

It is not especially formal, but it is also not slangy or casual in a marked way. It is just standard Italian.

That makes it a very useful model sentence.