Die simptoom en min eetlus maak my bekommerd.

Die is the Afrikaans definite article, usually equivalent to English the.

A few useful things to know:

• Afrikaans uses die for all genders, because Afrikaans does not have grammatical gender like German.
• Die can also be used with plural nouns, so context tells you whether it is singular or plural.
• Here, die simptoom means the symptom.

Literally, min eetlus means little appetite.

Breaking it down:

• min = little, not much
• eetlus = appetite

So the phrase naturally means:

• poor appetite
• little appetite
• lack of appetite in context

Afrikaans often uses simple quantity words like min in places where English might use a more abstract phrase.

Because min eetlus is being used as a general condition, not as a specific countable thing.

In Afrikaans, phrases like these often appear without an article:

• min eetlus = little appetite
• baie geld = a lot of money
• genoeg tyd = enough time

If you added die or 'n, it would change the nuance and usually sound less natural here. So min eetlus works well as an article-less noun phrase.

Eetlus is one word.

It is a compound noun:

• eet = eat
• lus = desire, liking

Together, eetlus means appetite.

This is very normal in Afrikaans: compound nouns are often written as one word.
But min eetlus is two words, because min is a separate modifier describing the noun eetlus.

The pattern maak + object + adjective means make someone/something + adjective.

So:

• maak my bekommerd = makes me worried

This is a very common Afrikaans structure. Similar examples:

• Dit maak my moeg = It makes me tired
• Dit maak my bly = It makes me happy
• Dit maak my kwaad = It makes me angry

So in your sentence, the symptom and poor appetite are the things that cause the speaker to feel worried.

Here, bekommerd is an adjective, meaning worried or concerned.

The sentence uses the pattern:

• iets maak iemand bekommerd
  = something makes someone worried

That is why bekommerd appears as an adjective, not as the main verb.

Compare:

• Ek is bekommerd = I am worried
• Dit maak my bekommerd = It makes me worried

Afrikaans does also have verbal ways to express this idea, but this adjective pattern is very natural and common.

Because Afrikaans verbs do not usually change form for person or number in the present tense.

So you get:

• Ek maak
• Jy maak
• Hy maak
• Ons maak
• Hulle maak

All use maak.

That means you do not have to worry about choosing a special plural verb form. Even though the subject is die simptoom en min eetlus, the verb is still simply maak.

This follows normal Afrikaans main-clause word order.

Afrikaans is a verb-second language in main clauses. That means the finite verb usually comes in the second position.

Here the first position is taken by the whole subject:

• Die simptoom en min eetlus

Then the verb comes next:

• maak

Then the rest follows:

• my bekommerd

So the structure is:

• Subject
  • finite verb
    • object
      • adjective

If something else came first, the verb would still stay second:

• Vandag maak die simptoom en min eetlus my bekommerd.

Yes, you could, but it is a slightly different structure.

• Dit bekommer my = It worries me
• Dit maak my bekommerd = It makes me worried

Both are possible. The version with maak ... bekommerd is very transparent for learners because it works like make + adjective in English.
The verb bekommer by itself can sound a little more formal or direct depending on context.

So the sentence you were given is perfectly natural and easy to understand.

Simptoom is singular, so it means one symptom.

Its plural is simptome.

So:

• die simptoom = the symptom
• die simptome = the symptoms

Whether singular or plural is correct depends on what the speaker means. If they are talking about one particular symptom plus poor appetite, simptoom is fine. If they mean several symptoms, then simptome would be more natural.

Grammatically, repeating the article is possible in some coordinated phrases, but here it would usually sound less natural.

Why?

• die simptoom refers to a specific symptom
• min eetlus is being treated more like a general condition or state

So the more natural wording is:

• Die simptoom en min eetlus maak my bekommerd.

If you said die min eetlus, it might sound as if you were referring to a very specific previously mentioned instance of poor appetite, which is usually not the intended idea here.