¿Podría usted decirme si la farmacia está abierta?

Podría is the conditional form of poder and makes the question more polite and less direct.

• ¿Puede usted decirme...? = Can you tell me...?
• ¿Podría usted decirme...? = Could you tell me...?

In English, could often sounds more polite than can, and it works similarly here.

No, usted is not strictly necessary because the verb form already shows formality.

You can say:

• ¿Podría usted decirme si la farmacia está abierta?
• ¿Podría decirme si la farmacia está abierta?

Both are correct. Including usted makes the sentence sound a little more explicit or formal.

Because me is attached to the infinitive decir.

• decir = to tell / to say
• me = to me

So decirme means to tell me.

In Spanish, object pronouns are often attached to infinitives:

• ayudarme = to help me
• llamarme = to call me
• decirme = to tell me

You could also say ¿Me podría decir...?, where me comes before the verb instead.

Yes. That is very natural and common.

Both are correct:

• ¿Podría usted decirme si la farmacia está abierta?
• ¿Me podría decir si la farmacia está abierta?

The second version often sounds a bit more natural in everyday speech.

Here si means if or whether.

It introduces an indirect yes/no question:

• si la farmacia está abierta = whether the pharmacy is open

This is different from sí with an accent, which means yes.

• si = if / whether
• sí = yes

Está abierta is used because being open is seen as a temporary state or condition.

• estar abierto/a = to be open
• estar cerrado/a = to be closed

So:

• La farmacia está abierta = The pharmacy is open

Es abierta would usually not be used for a shop being open.
Abre means opens, as in The pharmacy opens at 9:

• La farmacia abre a las nueve

Because abierta agrees with la farmacia, which is a feminine singular noun.

• la farmacia → feminine singular
• so the adjective is abierta

Compare:

• La farmacia está abierta
• El supermercado está abierto

The adjective changes to match the noun.

The written accents show which syllable is stressed.

• podría stresses the -rí-
• está stresses the last syllable

These accents are part of the correct spelling and sometimes help distinguish forms.

They are not optional in standard written Spanish.

Spanish uses both an opening and a closing question mark:

• ¿ ... ?

This tells the reader from the start that the sentence is a question.

So the correct punctuation is:

• ¿Podría usted decirme si la farmacia está abierta?

not just a final ?

It contains both.

The whole sentence is a direct question:

• ¿Podría usted decirme...?

Inside it, si la farmacia está abierta is an indirect yes/no question:

• whether the pharmacy is open

Spanish often uses si to introduce this kind of indirect question.

Normally, you would keep the article here:

• la farmacia

In Spanish, articles are used more often than in English. So la farmacia sounds natural, while farmacia on its own would usually sound incomplete in this sentence.

It is quite polite and formal.

The formality comes mainly from:

• podría instead of puede
• usted
• the overall structure ¿Podría usted decirme si...?

This would be appropriate for asking a stranger, especially in a polite public situation.

A less formal version could be:

• Perdone, ¿sabe si la farmacia está abierta?
• Oye, ¿sabes si la farmacia está abierta? (informal, only with people you address as *tú)*

This sentence is correct everywhere in the Spanish-speaking world, including Spain.

In Spain, it sounds polite and natural. A few regional preferences may differ, but the grammar is standard.

In Spain, you might also hear:

• Perdone, ¿sabe si la farmacia está abierta?
• Disculpe, ¿podría decirme si la farmacia está abierta?

All of these are normal.

Yes, but it changes the emphasis slightly.

• si la farmacia está abierta is the most neutral order
• si está abierta la farmacia is also possible, often with slightly more focus on abierta

Both are grammatical, but the original version is the most straightforward for learners.

In most of Spain, the c before i is pronounced like the th in thin:

• farmacia ≈ far-ma-thia

In many parts of Latin America, it is pronounced like an s:

• far-ma-sia

Both are correct in their own varieties. Since you asked about Spanish from Spain, the th sound is the usual one.

You can understand it word by word, but the most natural English translation may be a little different.

A rough word-for-word breakdown is:

• ¿Podría = Could
• usted = you
• decirme = tell me
• si = if / whether
• la farmacia = the pharmacy
• está abierta = is open

That gives:

• Could you tell me whether the pharmacy is open?

In natural English, you might also say:

• Could you tell me if the pharmacy is open?

So the structure matches English fairly well, but not always perfectly word for word.

A useful pattern is:

• ¿Podría + (usted) + infinitive + si + clause?

In this sentence:

• ¿Podría = Could you
• (usted) = formal you
• decirme = tell me
• si
• la farmacia está abierta = the pharmacy is open

You can reuse this pattern easily:

• ¿Podría decirme si hay un banco cerca? = Could you tell me if there is a bank nearby?
• ¿Podría decirme si el museo está abierto? = Could you tell me if the museum is open?
• ¿Podría decirme si pasa por aquí el autobús? = Could you tell me if the bus comes by here?