Η γιαγιά μου ανακουφίζεται όταν ακούει ότι όλα είναι καλά.

In Greek, you very often use the definite article with family members when you mean a specific person.

So:

• η γιαγιά μου = my grandmother
• ο πατέρας μου = my father
• η αδελφή μου = my sister

To an English speaker, the article can feel extra, but in Greek it is the normal pattern.

Because the short possessive pronouns in Greek usually come after the noun:

• η γιαγιά μου = my grandmother
• το σπίτι μου = my house
• οι φίλοι μου = my friends

This is the standard way to express possession with these unstressed forms. English does the opposite, so this is a very common thing for learners to notice.

ανακουφίζεται is:

• 3rd person singular
• present tense
• middle/passive form

It matches the subject η γιαγιά μου, so it means she is relieved / she feels relieved.

The ending -εται is a very common 3rd person singular ending in the middle/passive set of verb endings.

This is a very common Greek feature. A verb with middle/passive endings does not always mean a true passive like is being relieved by someone.

In Modern Greek, many verbs use these endings for meanings that are more like:

• experiencing a state
• undergoing a change
• acting in a way centered on the subject

So here ανακουφίζεται naturally means she feels relieved or she becomes relieved, even though the form looks passive to an English speaker.

ακούει is the present imperfective form, and here it gives a habitual or repeated sense:

• when/whenever she hears

So the sentence sounds like a general pattern: every time this happens, she feels relieved.

If you said όταν ακούσει, that would usually point more to a single complete future event:

• when she hears it
• when she has heard it

So ακούει fits the idea of a repeated, usual situation.

όταν means when and introduces a time clause.

In this sentence:

• Η γιαγιά μου ανακουφίζεται όταν ακούει...

the clause after όταν tells us when the main action happens.

Because the verb after όταν is in the present here, the sentence has a whenever kind of feeling, not just a one-time event.

Here ότι means that and introduces a content clause:

• ακούει ότι όλα είναι καλά
• she hears that everything is fine

This is different from ό,τι, which means whatever or anything that.

So:

• ότι = that
• ό,τι = whatever

That distinction is very important in writing.

This is a very natural Greek way to say everything is fine.

A few useful points:

• όλα is the neuter plural form of όλος
• here it means everything / all things
• καλά agrees with όλα in neuter plural form

So literally it is something like all things are good/fine, but idiomatically it means everything is fine.

Also, είναι is the same form for both singular and plural in the present tense, so you do not see a separate plural form of to be here.

Here it is best understood as a predicate adjective agreeing with όλα.

So:

• όλα = neuter plural
• καλά = neuter plural

That said, the form καλά also looks identical to the adverb well, which is why learners often get confused. In this sentence, though, it is part of the expression όλα είναι καλά = everything is fine.

Yes. Greek word order is more flexible than English word order.

The sentence as given is neutral and very natural:

• Η γιαγιά μου ανακουφίζεται όταν ακούει ότι όλα είναι καλά.

But Greek could also say:

• Όταν ακούει ότι όλα είναι καλά, η γιαγιά μου ανακουφίζεται.

That version puts more attention on the when-clause first. The meaning stays basically the same, but the focus or rhythm changes a little.

A rough pronunciation guide is:

ee ya-YA moo a-na-kou-FEE-ze-tai O-tan a-KOU-ee O-ti O-la EE-ne ka-LA

Main stresses:

• γιαγιά → stress on the last syllable
• ανακουφίζεται → stress on φί
• ακούει → stress on κού
• ότι → stress on ό
• είναι → stress on εί
• καλά → stress on the last syllable

A few pronunciation notes:

• η is pronounced ee
• για sounds roughly like ya
• αι in είναι sounds like e
• ου sounds like oo in food