La tua assenza mi dispiace.

The structure is:

• La tua assenza = your absence
• mi = to me
• dispiace = is displeasing / causes regret

So the sentence is built a bit like Your absence is displeasing to me, not like the English pattern I regret your absence.

This is the same kind of structure as mi piace (I like it, literally it is pleasing to me).
With dispiacere, the idea is the opposite: something causes sorrow, regret, or sadness.

In Italian, possessives usually go together with the definite article:

• la tua assenza = your absence
• il tuo libro = your book
• la mia casa = my house

So la tua assenza is the normal pattern.

A famous exception is with many singular family members:

• mia madre
• tuo fratello
• suo padre

But assenza is not a family noun, so the article la is required.

Because assenza is a feminine singular noun.

Italian possessives agree with the noun they describe, not with the owner.

So:

• il tuo libro = masculine singular
• la tua assenza = feminine singular
• i tuoi libri = masculine plural
• le tue assenze = feminine plural

Since assenza is feminine singular, the correct form is tua.

Mi means to me.

With dispiacere, the person who feels the regret or sadness is usually expressed as an indirect object:

• mi dispiace = it displeases me / I’m sorry
• ti dispiace = it displeases you
• gli dispiace = it displeases him
• le dispiace = it displeases her / you formal

So in La tua assenza mi dispiace, mi shows who is affected by the absence.

Here dispiace comes from dispiacere, which means something like:

• to displease
• to cause regret
• to make someone sorry
• to sadden

So La tua assenza mi dispiace means that your absence makes me sorry/sad.

This is different from using mi dispiace by itself, which very often means I’m sorry.

Examples:

• Mi dispiace. = I’m sorry.
• Mi dispiace la tua assenza. = Your absence saddens me / I’m sorry about your absence.

It is grammatical, but it may sound a bit formal, literary, or emotionally marked depending on context.

In everyday speech, Italians more often say:

• Mi dispiace per la tua assenza. = I’m sorry about your absence.

That version is very common and natural.

La tua assenza mi dispiace is understandable, but it puts more focus on your absence as the thing causing the feeling. It can sound more deliberate or expressive.

Yes. Italian word order is more flexible than English.

Possible versions include:

• La tua assenza mi dispiace.
• Mi dispiace la tua assenza.
• Mi dispiace per la tua assenza.

They do not all sound exactly the same.

• La tua assenza mi dispiace gives emphasis to your absence.
• Mi dispiace la tua assenza is possible, but less common in everyday speech.
• Mi dispiace per la tua assenza is the most idiomatic everyday choice.

So the sentence can change form depending on emphasis and style.

It can suggest both, depending on context.

A more literal sense is:

• Your absence saddens me
• Your absence causes me regret

A more natural English translation in many contexts might be:

• I’m sorry about your absence

So the exact English wording depends on how emotional or formal the situation is.

No, not exactly.

• La tua assenza mi dispiace focuses on the fact that the absence is regrettable or saddening.
• Mi manchi means I miss you.

So if you want to express personal longing, Mi manchi is usually stronger and more direct.

Compare:

• La tua assenza mi dispiace. = Your absence saddens me / I’m sorry you’re absent.
• Mi manchi. = I miss you.

You would change the possessive and possibly the pronoun:

• La Sua assenza mi dispiace.

Here:

• Sua = your in formal style
• La in La Sua assenza is still just the article the
• mi still means to me

If you wanted to say Your absence displeases/saddens you, using formal Lei, that would be different:

• La Sua assenza Le dispiace.

Notice the capital Le is sometimes used in writing for formality, though lowercase le is also common today.

You can say:

• La tua assenza mi è dispiaciuta.
• Mi è dispiaciuta la tua assenza.

This means:

• Your absence saddened me
• I was sorry about your absence

The past participle agrees with assenza, which is feminine singular, so you get dispiaciuta.

Compare:

• Mi dispiace = present
• Mi è dispiaciuta = past, feminine singular subject

A rough pronunciation is:

la TOO-ah as-SEN-tsa mee dee-SPYA-che

A few notes:

• tua is two syllables: TU-a
• assenza has the stress on sen
• dispiace sounds like dee-SPYA-che
• ci before a/o/u gives a ch sound, so -piace sounds like -pya-che

A more IPA-like version is:

[la ˈtu.a asˈsɛntsa mi disˈpjatʃe]

Yes, but the meaning becomes less specific.

• Mi dispiace. usually means I’m sorry.
• La tua assenza mi dispiace. specifically says what is causing the feeling.

So Mi dispiace is fine if the context already makes the reason clear.
If you want to mention the reason directly, you keep la tua assenza.