Learn Russian: В ноябре плохая погода, поэтому никто не хочет ехать в отпуск. - In November the weather is bad, so nobody wants to go on vacation.

To say 'in a certain month', Russian uses the preposition в plus the Prepositional case. The dictionary form ноябрь (November) ends in a soft sign (-ь). To make it Prepositional, that -ь changes to an -е, giving us в ноябре.

Why does the sentence say никто не хочет ('nobody doesn't want')? Isn't that a double negative?

Yes, and that is exactly how Russian works! Whenever you use a negative word like никто (nobody) or ничего (nothing), you must also put не before the verb. Unlike English, Russian requires these double negatives.

Why use ехать for 'to go' instead of идти?

Russian has different verbs for going by foot (идти) versus going by vehicle (ехать). Because going on vacation almost always involves taking a car, train, or plane, ехать is the natural choice here.

The sentence has в ноябре and в отпуск. Why do they use different cases after the same preposition в?