En esa empresa, hablamos informalmente, pero siempre con respeto.

En esa empresa means in that company or at that company.

Spanish often uses en where English uses either in or at for places and workplaces:

• en la oficina = at/in the office
• en la empresa = at/in the company

So En esa empresa sets the context first: it tells you where this way of speaking happens.

Esa means that, while esta means this.

The choice depends on how the speaker sees the company:

• esta empresa = this company, usually one felt to be closer to the speaker
• esa empresa = that company, a bit more removed
• aquella empresa = that company over there / that company further away, sometimes more distant in time or feeling

So esa empresa suggests the speaker is referring to a specific company, but not presenting it as this one here.

Spanish often leaves out subject pronouns because the verb ending already shows who the subject is.

• hablamos = we speak / we talk
• The ending -amos tells you the subject is we (nosotros / nosotras)

So:

• Hablamos informalmente = We speak informally
• Nosotros hablamos informalmente is also possible, but it adds emphasis or contrast

Leaving the pronoun out is the normal, natural choice.

In this sentence, hablamos means we speak in a general or habitual sense.

The present tense in Spanish can cover:

• habitual actions: we speak
• current actions, depending on context: we are speaking

Here, because the sentence describes a general workplace culture, the meaning is habitual:

• En esa empresa, hablamos informalmente = At that company, we speak informally

It is not mainly describing what is happening right now at this exact moment.

Informalmente is an adverb meaning informally. It describes how they speak.

It comes from the adjective informal:

• informal = informal
• informalmente = informally

Spanish often forms adverbs by adding -mente to the feminine form of an adjective:

• rápida → rápidamente
• clara → claramente
• informal → informalmente

So hablamos informalmente means we speak in an informal way.

Yes. Both are correct:

• Hablamos informalmente
• Hablamos de manera informal

They mean basically the same thing.

The version with informalmente is a bit more compact and natural in many cases.
De manera informal is slightly more descriptive and can sound a little more formal or explanatory.

Pero means but. It introduces a contrast.

The contrast here is:

• they speak informally
• but still with respect

This is a very common idea in Spanish: informality does not mean rudeness.

So pero siempre con respeto shows an important limit or condition:

• the tone is relaxed
• the attitude remains respectful

Both are possible, but con respeto is more natural and common here.

Compare:

• siempre con respeto = always with respect
• siempre respetuosamente = always respectfully

Con respeto sounds very idiomatic in this kind of statement about behavior or workplace culture.
Respetuosamente is correct, but it can sound a bit more formal or less natural in everyday speech.

Siempre means always, and here it emphasizes that respect is constant.

The idea is:

• they may speak informally
• but they always do so with respect

So siempre is tied to the whole phrase con respeto:

• siempre con respeto = always with respect

It highlights a rule or principle, not just a one-time action.

Both are possible, but siempre con respeto is the more natural order here.

Spanish word order is flexible, but the usual version places siempre before the phrase it emphasizes:

• siempre con respeto

Con respeto siempre is understandable, but it sounds less neutral and may feel more emphatic or stylistically marked.

The commas help separate the introductory phrase and the contrast.

• En esa empresa, sets the scene first
• hablamos informalmente, pero... separates the main statement from the contrast introduced by pero

So the commas make the sentence easier to read and reflect natural pauses.

The first comma is especially common after an introductory phrase like En esa empresa.

Yes, but the meaning changes slightly.

• En esa empresa, hablamos informalmente... = At that company, we speak informally...
• En esa empresa, se habla informalmente... = At that company, people speak informally... / informal speech is used there...

Hablamos includes the speaker as part of the group.
Se habla is more impersonal and general.

So if the speaker works there and is including themself, hablamos is the better choice.

Usually, yes, in this context.

Empresa commonly means:

• company
• business
• firm

In En esa empresa, it refers to a workplace or business organization.
Depending on context, English might translate it as company, firm, or even workplace, but company is the most direct match here.

It can match either to speak or to talk in English, depending on translation style.

• hablamos informalmente could be translated as we speak informally
• or we talk informally

Both are fine.
In this sentence, the focus is on the style or register of communication, so speak may sound slightly closer in tone, but talk is also natural.

It sounds natural, clear, and professional.

It suggests a workplace culture where:

• communication is relaxed or not overly formal
• respect is still important

So the sentence gives a balanced message: friendly but professional.