Learn Spanish (Spain): No tengo interés alguno en ese trabajo.

When alguno is placed after a singular noun in a negative sentence, it takes on a negative meaning equivalent to ninguno. In this position, it translates well to "whatsoever" or "at all," adding strong emphasis to your lack of interest.

Could I say No tengo ningún interés en ese trabajo instead?

Yes, that is perfectly correct and very common. However, placing alguno after the noun (interés alguno) sounds slightly more emphatic and formal than using ningún interés. It highlights the absolute zero level of interest you have.

Does the word order matter here for alguno?

It matters a lot! To mean "none whatsoever", alguno must come strictly after the noun. If you put the shortened form algún before the noun (No tengo algún interés), it sounds grammatically incorrect because algún means "some", which clashes with the negative word No.

Why is the preposition en used after interés here?

Just like in English where we say "interest in", Spanish uses interés en when referring to an interest in a specific thing, job, or activity. You might also hear interés por in some contexts, but en is the most standard choice for a job or position.