Learn Spanish (Latin America): ¿Te resulta familiar este vecindario? - Does this neighborhood seem familiar to you?

Both verbs work and mean "to seem" when combined with an indirect object pronoun like te. However, using resultar as a linking verb often emphasizes the subjective impression or effect something has on you upon encountering it. It translates well to "Does it strike you as..." or "Does it turn out to be...".

Why is the subject este vecindario at the very end of the sentence?

Verbs used for subjective evaluations, like resultar, parecer, or gustar, often trigger a flipped word order. The thing being evaluated (este vecindario) is the grammatical subject, but it feels natural at the end of the sentence. You could say ¿Este vecindario te resulta familiar?, but placing the subject last is extremely common, especially in questions.

How would this sentence change if we were talking about multiple neighborhoods?

The subject would become estos vecindarios. Because the subject is now plural, the verb must become resultan and the adjective must become familiares. The sentence would be: ¿Te resultan familiares estos vecindarios?. The pronoun te stays the same because it still refers to the same person.

Why not just use ser or estar to say the neighborhood is familiar?