kono kuriimu ha te ni mo kao ni mo nureru.

Those spaces are just for learners. Normal Japanese would be written as:

このクリームは手にも顔にもぬれる。
or, with kanji, このクリームは手にも顔にも塗れる。

Japanese normally does not put spaces between words the way English does.

は marks the topic.

So このクリームは means something like:

• as for this cream
• this cream, ...

The sentence is talking about what this cream is like or what can be done with it. Using は makes this cream the thing under discussion.

A version with が is also possible in some contexts, but は is very natural when describing a product’s feature.

Here, に marks the place or target where the cream is applied.

So:

• 手に塗る = apply it to the hands
• 顔に塗る = apply it to the face

In this sentence, the cream is the topic, and 手 and 顔 are the body parts it can be used on.

Because も attaches to each item separately.

So:

• 手にも = also on the hands
• 顔にも = also on the face

Together, 手にも顔にも means:

• on the hands and also on the face
• more naturally, on both the hands and the face

Repeating も is normal in this pattern.

It is the potential form of 塗る.

• dictionary form: 塗る
• potential form: 塗れる

So 塗れる means:

• can apply
• can be put on
• is applicable/useable on

In this sentence, it does not mean passive.
The passive of 塗る would be 塗られる.

It often means more than simple physical possibility.

With products like cream, medicine, or sunscreen, 塗れる commonly suggests:

• it is okay to use there
• it is suitable for that area
• it can be applied there

So this kind of sentence can sound like product-label language: This cream can be used on both the hands and the face.

Japanese often leaves the doer unstated when it is obvious or unimportant.

Here, the focus is on the cream, not on the person using it. The meaning is basically:

• someone can apply this cream to the hands and face
• this cream is usable on the hands and face

It could mean you, one, or people in general.

Two reasons:

1. Japanese has no articles like a or the.
2. Japanese often omits possessives when the owner is obvious, especially with body parts.

So 手 and 顔 here naturally mean the user's hands and face, without needing to say your.

This is very common in Japanese.

Japanese nouns usually do not show singular vs. plural clearly.

So 手 can mean:

• hand
• hands

In this sentence, English would normally say hands, because that sounds more natural for cream use.
Likewise, 顔 is just face here.

Yes, but the nuance changes a little.

• 手と顔に塗れる = can be applied to the hands and face
• 手にも顔にも塗れる = can be applied to the hands and also to the face / to both hands and face

The version with も gives a stronger also / both feeling. It is very natural when emphasizing that the cream works for more than one area.

Yes. A more directly action-focused sentence would be:

• このクリームを手にも顔にも塗れる
• 手にも顔にもこのクリームを塗れる

That means can apply this cream to both the hands and the face.

But the original sentence, このクリームは手にも顔にも塗れる, sounds more like describing a property of the cream itself, which is why it feels natural in product descriptions.