Breakdown of kono mondai wa anzen ni kanrenshite iru.
Questions & Answers about kono mondai wa anzen ni kanrenshite iru.
は marks 問題 as the topic of the sentence.
So この問題は means something like:
- As for this issue...
- This issue...
In English, we often just start with the subject directly, but Japanese often separates the topic from the rest of the statement.
You could think of the structure as:
- この問題は = as for this issue
- 安全に関連している = is related to safety
