Tato otázka mě zajímá.

• Tato = this
• otázka = question
• mě = me
• zajímá = interests / is of interest to

So the sentence is literally This question interests me, which is the natural Czech way to express I’m interested in this question.

Because otázka is a feminine singular noun.

In Czech, words like this must agree with the noun’s gender, number, and case.

For ten / this/that-type words, the singular nominative forms are:

• ten for masculine
• ta / tato for feminine
• to / toto for neuter

Since otázka is feminine singular, the correct form here is tato.

Both can mean that question or this question depending on context, but there is a nuance:

• ta otázka = more common, less emphatic, often just that/this question
• tato otázka = more explicit, a bit more formal or more clearly this particular question

So Tato otázka mě zajímá sounds slightly more pointed or deliberate than Ta otázka mě zajímá.

Otázka is in the nominative singular because it is the subject of the sentence.

The thing doing the interesting is the question, not me.

So the structure is:

• Tato otázka = subject, nominative
• mě = object, accusative
• zajímá = verb

Czech uses this structure where English often uses I am interested in...

Because mě is the object form of I.

• já = I (subject form)
• mě / mne = me (object form)

In this sentence, I am not the subject. The subject is this question. So Czech uses mě:

• Tato otázka mě zajímá = This question interests me

Using já here would be grammatically wrong.

Mě is in the accusative case.

The verb zajímat takes a direct object: someone or something is interested by something.

So:

• otázka = nominative subject
• mě = accusative object

You can think of it as:

• The question interests me
• Mě is the person being affected by the question’s interestingness

Because it agrees with the subject tato otázka, which is singular.

In Czech, verbs in the present tense agree with the subject in number (and sometimes person).

Here the subject is:

• tato otázka = this question = singular

So the verb is singular:

• zajímá = interests

If the subject were plural, the verb would change:

• Tyto otázky mě zajímají = These questions interest me

Czech often expresses this idea differently.

A very common Czech pattern is:

• X mě zajímá = X interests me

So instead of saying I am interested in X, Czech often says X interests me.

That is why Tato otázka mě zajímá is completely natural Czech, even though English prefers a different structure.

Both can be translated as I’m interested in this question, but they are not identical.

• Tato otázka mě zajímá = This question interests me

  • describes your feeling or reaction
  • often sounds more immediate and natural in everyday use

• Zajímám se o tuto otázku = I am interested in / I take an interest in this question

  • focuses more on your active interest or engagement
  • can suggest ongoing involvement or concern

So:

• Tato otázka mě zajímá = this question catches my interest
• Zajímám se o tuto otázku = I concern myself with / I have an interest in this question

Yes. Czech word order is flexible, and changing it usually changes emphasis, not the basic meaning.

For example:

• Tato otázka mě zajímá. = neutral
• Mě zajímá tato otázka. = emphasizes me or contrasts with someone else
• Zajímá mě tato otázka. = very natural; often sounds slightly more flowing in conversation

All of these can mean basically the same thing, but the focus shifts.

You can also say mne, but mě is much more common in everyday speech.

• mě = normal, common spoken and written form
• mne = more formal, literary, or emphatic

So:

• Tato otázka mě zajímá = the usual choice
• Tato otázka mne zajímá = correct, but more formal or stylistically marked

A simple learner-friendly approximation is:

TA-to OTAAZ-ka mye za-YEE-maa

A few useful notes:

• tato = stress on the first syllable: TA-to
• otázka = stress on O, even though á is long
• mě sounds roughly like mye
• zajímá has a long í and long á

Also remember: Czech stress is usually on the first syllable of the word.

It can mean question, but depending on context it can also mean something like issue, matter, or problem/question under discussion.

So Tato otázka mě zajímá could mean:

• This question interests me
• This issue interests me

The exact English translation depends on context.