To express "no matter how much," use por más que or por mucho que.
When describing an experienced reality or a known fact (like an ongoing or past action), use the indicative.
| No matter how much we used the pesticide, the pest wouldn't disappear. | Por más que usábamos el pesticida, la plaga no desaparecía. |
| No matter how much fertilizer they pour, the field is not fertile. | Por más que echan abono, el campo no es fértil. |
When referring to a hypothetical situation, a future possibility, or an unknown outcome, use the subjunctive.
| No matter how much you use the pesticide, this pest will destroy the harvest. | Por mucho que uses el pesticida, esta plaga destruirá la cosecha. |
| No matter how much they use the expensive fertilizer, the seed does not grow. | Por mucho que usen el fertilizante caro, la semilla no crece. |
Notice how the mood changes the focus from a known fact to a hypothetical scenario:
| No matter how much they removed the weeds with the shovel, they always grew. | Por más que sacaban la maleza con la pala, siempre crecía. |
| No matter how much you dig with the shovel, the weeds will return. | Por mucho que caves con la pala, la maleza volverá. |
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