Learn Portuguese (Portugal): A farmácia fica entre o café e o banco. - The pharmacy is between the café and the bank.

In Portuguese, the verb ficar is used to describe the permanent location of a building, city, or landmark. While you use estar for temporary locations (like where a person is right now), ficar is the natural choice for the permanent address of a place like a farmácia.

Does the preposition entre change if the nouns after it are plural or feminine?

No, entre (meaning between or among) is an invariable word. It does not change its spelling to match gender or number. It stays exactly the same whether it comes before a masculine word like o café or a feminine word.

Do I always need to repeat the article o for both café and banco?

Yes, it is required in Portuguese to keep the definite articles for both nouns in this context. While in English you might sometimes say "between the cafe and bank", Portuguese is stricter and requires the article o before both specific places.

Does café mean the physical shop here, or just the drink?

It means the shop! Just like in English, o café refers to both the hot beverage you drink and the physical establishment or coffee shop where you go to buy it.