Learn Polish: Mimo że to jest dziwne, bardzo się staram. - Even though this is strange, I am trying very hard.

Both mean "although" or "even though" and you can use them interchangeably in this sentence! mimo że sometimes feels a little stronger, closer to "despite the fact that," but grammatically they do the exact same job here.

Why is dziwne ending in -e here?

It ends in -e because it is in the neuter form. It describes the pronoun to (this/it), which is always treated as grammatically neuter. If you were describing a masculine word, you would use dziwny.

I know próbować also means "to try". Can I say bardzo próbuję instead of bardzo się staram?

Not quite. próbować means to attempt or test something out (like trying a new food or seeing if a key works). starać się means to make an effort or work hard at something. Since you are putting in a lot of effort here, starać się is the natural choice.

Why is there a comma after dziwne?

In Polish, you must always use a comma to separate a subordinate clause (the part starting with mimo że) from the main clause (bardzo się staram). English comma rules are sometimes flexible, but Polish strictly requires this punctuation.