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Moi, l'incertitude me rend anxieux.

Moi, l'incertitude me rend anxieux.
Me, uncertainty makes me anxious.
From Lesson 356:Causing a state (rendre + adjectif)·French

Questions & Answers about Moi, l'incertitude me rend anxieux.

Why is it me rend anxieux instead of me fait anxieux for "makes me anxious"?
In French, when you want to say that something "makes" a person or thing into a certain state (followed by an adjective), you must use rendre. You use faire when it is followed by a verb (an action), like faire rire (to make someone laugh). Since anxieux is an adjective, rendre is the correct choice here.
Why does "uncertainty" have an article (l'incertitude) here when it doesn't in the English sentence?
In French, abstract nouns and general concepts like uncertainty, love, or life require a definite article (le, la, l', or les). Since the speaker is talking about uncertainty in a general sense, it becomes l'incertitude.
What is the purpose of starting the sentence with Moi?
Adding Moi at the beginning is a very common French way to emphasize who is being talked about, similar to saying "As for me" or "Personally" in English. It creates a strong contrast, implying that while other people might handle uncertainty well, it makes this specific speaker anxious.
If a woman were saying this sentence, would the adjective change?
Yes! The adjective anxieux describes the direct object me (which refers to the speaker, Moi). If a woman is speaking, the adjective must agree with her gender, so she would say Moi, l'incertitude me rend anxieuse.

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