Al bajar del autobús, camina directamente hasta la farmacia.

Al + infinitive is a very common Spanish structure meaning when, upon, or on doing something.

So al bajar del autobús means something like:

• when you get off the bus
• upon getting off the bus

It is especially common in instructions, directions, and written guides because it is short and efficient.

You could also say cuando bajes del autobús, which is also very natural. But al bajar sounds a bit more compact and formulaic.

Here, del is the contraction of de + el.

So:

• de el autobús → del autobús

After bajar, Spanish often uses de when you mean get off something:

• bajar del autobús = get off the bus
• bajar del tren = get off the train

So del autobús is the normal form here.

Yes. Bajar and bajarse can both be used for getting off a vehicle.

• bajar del autobús
• bajarse del autobús

Both are natural. The version in your sentence, al bajar del autobús, sounds a little more neutral and concise, which fits written directions well.

If you wanted to make it more directly tied to you, you might hear:

• al bajarte del autobús

That sounds slightly more personal.

Yes. In this sentence, camina is an informal singular command, addressed to tú.

So it means walk.

For a regular -ar verb, the tú affirmative command looks the same as the él/ella present form:

• caminar → camina

Context tells you it is a command here, not a statement.

Compare:

• Camina directamente hasta la farmacia. = Walk straight to the pharmacy.
• Él camina directamente hasta la farmacia. = He walks straight to the pharmacy.

If you wanted the formal singular command, it would be:

• Camine directamente hasta la farmacia.

Spanish often leaves out subject pronouns because the verb ending already shows who the subject is.

So instead of saying:

• Tú camina directamente...

Spanish normally just says:

• Camina directamente...

Including tú would usually add emphasis, contrast, or emotion. In ordinary instructions, it is normally omitted.

Hasta often means up to, as far as, or all the way to. In directions, it works very naturally to show the endpoint of movement.

So camina directamente hasta la farmacia gives the idea of:

• keep going directly until you reach the pharmacy

With directions, this feels very natural.

A la farmacia is also possible in many contexts, but hasta la farmacia focuses more clearly on the route ending at that point.

Directamente means directly or straight.

In this sentence, it modifies camina and tells you how to walk: go there without detours or intermediate stops.

So the idea is:

• walk straight to the pharmacy
• go directly to the pharmacy

Its position is also natural here:

• camina directamente hasta la farmacia

That is a very normal word order in Spanish.

La farmacia suggests a specific pharmacy that is known from the situation: the one nearby, the one on the route, or the one the speaker has in mind.

Compare:

• la farmacia = the pharmacy, a specific one
• una farmacia = a pharmacy, any one

In directions, Spanish often uses the definite article when the destination is understood or identifiable.

Saying just farmacia without an article would not be correct here in standard Spanish.

Yes, absolutely.

• Al bajar del autobús, camina...
• Cuando bajes del autobús, camina...

Both are correct and natural.

The difference is mainly one of style:

• al + infinitive = more compact, often used in instructions
• cuando bajes = more explicit and personal

A useful extra point: in this kind of future-oriented instruction, Spanish normally prefers cuando bajes, not cuando bajas.

So if you rewrite it with cuando, the most natural version is:

• Cuando bajes del autobús, camina directamente hasta la farmacia.

Because Spanish stress rules require it.

Words ending in a vowel, n, or s are normally stressed on the second-to-last syllable. But autobús is stressed on the last syllable: au-to-BÚS.

The accent mark shows that unusual stress.

A useful detail: in the plural, the accent disappears:

• autobús
• autobuses

That is because autobuses already follows the normal stress pattern without needing a written accent.

Because Al bajar del autobús is an introductory clause before the main instruction.

The comma helps separate:

• the time/action background: Al bajar del autobús
• the main command: camina directamente hasta la farmacia

This punctuation is very natural and standard in written Spanish. It makes the sentence easier to read.