الصيدلي هيسال عن التداخل الدوائي مع المضاد الحيوي.

A natural pronunciation would be something like:

eṣ-ṣeidali hayisʔal ʿan et-tadākhul ed-dawāʔi maʿ el-moḍādd el-ḥayawi

A simpler learner-friendly version is:

es-seidali hayis'al ʿan et-tadakhul ed-dawa'i maʿ el-modadd el-hayawi

A few notes:

• الص in الصيدلي sounds like a doubled s sound: es-seidali
• عن is ʿan, with the Arabic letter ع
• مع is maʿ, also ending with ع
• The medical words here are fairly formal, even though the verb form is Egyptian colloquial

هيسال means he will ask.

It is made of:

• هـ / هيـ = a future marker in Egyptian Arabic
• يسأل = he asks

So:

• يسأل = he asks
• هيسأل / هيسال = he will ask

In Egyptian Arabic, this future marker is very common in speech.

Because informal Arabic spelling often drops the hamza (ء) in everyday writing.

More formal spelling would be:

• هيسأل

But in casual writing, many people write:

• هيسال

The pronunciation still usually includes a little break or glottal stop, so learners should understand that both spellings point to the same word.

Because Arabic allows more than one natural word order.

Here, starting with الصيدلي puts the topic first:

• الصيدلي هيسال... = The pharmacist will ask...

This feels like introducing or highlighting the pharmacist as the person who will do the action.

You could also see a verb-first structure in Arabic, but this subject-first order is very normal, especially in spoken Arabic.

Because سأل / يسأل عن means to ask about or to inquire about.

So:

• يسأل عن التداخل الدوائي = he asks about the drug interaction

This is important because سأل can work in different ways:

• سأل الصيدلي = he asked the pharmacist
• سأل عن التداخل = he asked about the interaction

So in this sentence, عن tells you the thing being asked about.

Because مع means with, and here it connects the interaction to the antibiotic.

So:

• التداخل الدوائي مع المضاد الحيوي = the drug interaction with the antibiotic

The structure is:

• هيسال عن... = he will ask about...
• التداخل الدوائي مع المضاد الحيوي = the drug interaction with the antibiotic

So the whole idea is that the pharmacist will ask about whether there is an interaction involving the antibiotic.

Because ال is the Arabic definite article, meaning the.

In this sentence, you have:

• الصيدلي = the pharmacist
• التداخل = the interaction
• الدوائي = the drug-related / medicinal
• المضاد الحيوي = the antibiotic

Arabic often uses definiteness in places where English might be a little looser.

Also, when a noun is definite and it has an adjective, the adjective also becomes definite. That is why you get:

• التداخل الدوائي
• المضاد الحيوي

not just one word with ال.

This is because of sun-letter assimilation.

When ال comes before certain consonants, the l sound disappears and the next consonant is doubled.

For example:

• الصيدلي is pronounced eṣ-ṣeidali
• التداخل is pronounced et-tadākhul
• الدوائي is pronounced ed-dawāʔi

But with letters that are not sun letters, the l stays:

• المضاد = el-moḍādd
• الحيوي = el-ḥayawi

So the spelling stays ال, but the pronunciation changes depending on the next letter.

Because حيوي is an adjective describing مضاد, and in Arabic adjectives match the noun they describe.

So:

• مضاد حيوي = an antibiotic
• المضاد الحيوي = the antibiotic

This matching happens in definiteness, gender, and number.

Literally, the phrase is something like:

• the anti-biotic

But naturally, it just means the antibiotic.

الدوائي means something like drug-related, medicinal, or pharmaceutical.

It comes from دواء, meaning medicine or drug.

So:

• التداخل الدوائي = drug interaction
• literally: the medicinal/drug-related interaction

This is a fairly formal or technical adjective, which is why the sentence sounds partly medical or professional.

It is a mix, and that is very normal.

• هيسال is clearly Egyptian colloquial
• التداخل الدوائي and المضاد الحيوي are more formal or technical medical vocabulary

So the sentence sounds like something an Egyptian speaker might say in a medical or pharmacy context: colloquial grammar plus formal terminology.

That kind of mix is extremely common in educated spoken Arabic, especially in healthcare, business, news, and technical topics.