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De nada, señora.

De nada, señora.
You are welcome, ma'am.
From Lesson 34:Prepositional pronouns (mí, ti)·Spanish (Latin America)

Questions & Answers about De nada, señora.

Why does de nada mean "you're welcome" if nada means "nothing"?
Literally, de nada means "of nothing". It is used just like "it's nothing" or "think nothing of it" in English as a polite way to reply when someone thanks you for a favor.
Since the current lesson is about pronouns after prepositions like de and a, could I add one and say de nada a usted?
No, you would not add a pronoun like usted to this phrase. De nada is a fixed, set expression that stands perfectly on its own. Adding a respectful title like señora is the best and most natural way to direct your politeness to a specific person.
When exactly should I use señora instead of just saying de nada?
Adding señora makes the phrase extra polite. It is similar to "ma'am" or "Mrs." in English. You use it to show respect when speaking to an older woman, a woman you know is married, or a female stranger or customer.

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