Chinese, Mandarin

Spanish

English

Hindi

Arabic

Portuguese

Bengali

Russian

Japanese

Punjabi

German

Javanese

Malay

Telugu

Vietnamese

Korean

French

Marathi

Tamil

Urdu

Turkish

Italian

Chinese, Yue / Cantonese

Thai

Gujarati

Chinese, Jin

Chinese, Min Nan

Persian, Dari

Persian, Western

Polish

Pashto

Kannada

Chinese, Xiang

Malayalam

Sundanese

Hausa

Odia

Burmese

Chinese, Hakka

Ukrainian

Bihari, Bhojpuri

Tagalog

Yoruba

Bihari, Maithili

Uzbek

Sindhi

Amharic

Fula

Romanian

Oromo

Igbo

Azerbaijani

Chinese, Gan

Dutch

Kurdish, Central

Kurdish, Northern

Kurdish, Southern

Malagasy

Lahnda, Saraiki

Nepali

Sinhalese

Chittagonian

Zhuang

Khmer

Turkmen

Assamese

Madurese

Somali

Marwari

Bihari, Magahi

Haryanvi

Hungarian

Chhattisgarhi

Greek, Modern

Chewa

Dakhini

Akan, Twi

Akan, Fante

Kazakh

Chinese, Min Bei

Sylheti

Zulu

Czech

Kinyarwanda

Marwari, Dhundhari

Haitian Creole

Chinese, Min Dong

Ilocano

Quechua

Kirundi

Swedish

Hmong

Shona

Uyghur

Hiligaynon

Mossi

Xhosa

Belarusian

Balochi

Psychology

<OpenstaxParagraph>
	Now that we have learned about the basic structures of the neuron and the role that these structures play in neuronal communication, let’s take a closer look at the signal itself—how it moves through the neuron and then jumps to the next neuron, where the process is repeated.
</OpenstaxParagraph>
<OpenstaxParagraph>
	We begin at the neuronal membrane. The <OpenstaxTerm>neuron</OpenstaxTerm> exists in a fluid environment—it is surrounded by extracellular fluid and contains intracellular fluid (i.e., cytoplasm). The neuronal membrane keeps these two fluids separate—a critical role because the electrical signal that passes through the neuron depends on the intra- and extracellular fluids being electrically different. This difference in charge across the membrane, called the <OpenstaxTerm>membrane potential</OpenstaxTerm>, provides energy for the signal.
</OpenstaxParagraph>
<OpenstaxParagraph>
	The electrical charge of the fluids is caused by charged molecules (ions) dissolved in the fluid. The semipermeable nature of the neuronal membrane somewhat restricts the movement of these charged molecules, and, as a result, some of the charged particles tend to become more concentrated either inside or outside the cell.
</OpenstaxParagraph>
<OpenstaxParagraph>
	Between signals, the neuron membrane’s potential is held in a state of readiness, called the <OpenstaxTerm>resting potential</OpenstaxTerm>. Like a rubber band stretched out and waiting to spring into action, ions line up on either side of the cell membrane, ready to rush across the membrane when the neuron goes active and the membrane opens its gates. Ions in high-concentration areas are ready to move to low-concentration areas, and positive ions are ready to move to areas with a negative charge.
</OpenstaxParagraph>
<OpenstaxParagraph>
	In the resting state, sodium (Na+) is at higher concentrations outside the cell, so it will tend to move into the cell. Potassium (K+), on the other hand, is more concentrated inside the cell, and will tend to move out of the cell (<a href="#CNX_Psych_03_02_NaKConc">Figure 3.10</a>). In addition, the inside of the cell is slightly negatively charged compared to the outside, due to the activity of the sodium-potassium pump. This pump actively transports three sodium ions out of the cell for every two potassium ions in, creating a net negative charge inside the cell. This provides an additional force on sodium, causing it to move into the cell.
</OpenstaxParagraph>
<OpenstaxFigure id="CNX_Psych_03_02_NaKConc" src="https://openstax.org/apps/archive/20240226.174525/resources/64f9607dcac413179b9f7d0f596305bab38f3800" alt="A close-up illustration depicts the difference in charges across the cell membrane, and shows how Na+ and K+ cells concentrate more closely near the membrane." mediaType="image/jpg" width="975" height="368" />
<OpenstaxFigureText width="975">
	Figure 3.10 At resting potential, Na+ (blue pentagons) is more highly concentrated outside the cell in the extracellular fluid (shown in blue), whereas K+ (purple squares) is more highly concentrated near the membrane in the cytoplasm or intracellular fluid. Other molecules, such as chloride ions (yellow circles) and negatively charged proteins (brown squares), help contribute to a positive net charge in the extracellular fluid and a negative net charge in the intracellular fluid.
</OpenstaxFigureText>
<OpenstaxParagraph>
	From this resting potential state, the neuron receives a signal and its state changes abruptly (<a href="#CNX_Psych_03_02_ActionP">Figure 3.11</a>). When a neuron receives signals at the dendrites—due to neurotransmitters from an adjacent neuron binding to its receptors—small pores, or gates, open on the neuronal membrane, allowing Na+ ions, propelled by both charge and concentration differences, to move into the cell. With this influx of positive ions, the internal charge of the cell becomes more positive. If that charge reaches a certain level, called the <OpenstaxTerm>threshold of excitation</OpenstaxTerm>, the neuron becomes active and the action potential begins.
</OpenstaxParagraph>
<OpenstaxParagraph>
	Many additional pores open, causing a massive influx of Na+ ions and a huge positive spike in the membrane potential, the peak action potential. At the peak of the spike, the sodium gates close and the potassium gates open. As positively charged potassium ions leave, the cell quickly begins repolarization. At first, it hyperpolarizes, becoming slightly more negative than the resting potential, and then it levels off, returning to the resting potential.
</OpenstaxParagraph>
<OpenstaxFigure id="CNX_Psych_03_02_ActionP" src="https://openstax.org/apps/archive/20240226.174525/resources/3d084f9cec67b33ae2c686fb2238e8ef9f1fe1f9" alt="A graph shows the increase, peak, and decrease in membrane potential. The millivolts through the phases are approximately -70mV at resting potential, -55mV at threshold of excitation, 30mV at peak action potential, 5mV at repolarization, and -80mV at hyperpolarization." mediaType="image/jpg" width="487" height="352" />
<OpenstaxFigureText width="487">
	Figure 3.11 During the action potential, the electrical charge across the membrane changes dramatically.
</OpenstaxFigureText>
<OpenstaxParagraph>
	This positive spike constitutes the <OpenstaxTerm>action potential</OpenstaxTerm>: the electrical signal that typically moves from the cell body down the axon to the axon terminals. The electrical signal moves down the axon with the impulses jumping in a leapfrog fashion between the Nodes of Ranvier. The Nodes of Ranvier are natural gaps in the myelin sheath. At each point, some of the sodium ions that enter the cell diffuse to the next section of the axon, raising the charge past the threshold of excitation and triggering a new influx of sodium ions. The action potential moves all the way down the axon in this fashion until reaching the terminal buttons.
</OpenstaxParagraph>
<OpenstaxParagraph>
	The action potential is an <OpenstaxTerm>all-or-none</OpenstaxTerm> phenomenon. In simple terms, this means that an incoming signal from another neuron is either sufficient or insufficient to reach the threshold of excitation. There is no in-between, and there is no turning off an action potential once it starts. Think of it like sending an email or a text message. You can think about sending it all you want, but the message is not sent until you hit the send button. Furthermore, once you send the message, there is no stopping it.
</OpenstaxParagraph>
<OpenstaxParagraph>
	Because it is all or none, the <OpenstaxTerm>action potential</OpenstaxTerm> is recreated, or propagated, at its full strength at every point along the axon. Much like the lit fuse of a firecracker, it does not fade away as it travels down the axon. It is this all-or-none property that explains the fact that your brain perceives an injury to a distant body part like your toe as equally painful as one to your nose.
</OpenstaxParagraph>
<OpenstaxParagraph>
	As noted earlier, when the action potential arrives at the terminal button, the synaptic vesicles release their neurotransmitters into the synaptic cleft. The neurotransmitters travel across the synapse and bind to receptors on the dendrites of the adjacent neuron, and the process repeats itself in the new neuron (assuming the signal is sufficiently strong to trigger an action potential). Once the signal is delivered, excess neurotransmitters in the synaptic cleft drift away, are broken down into inactive fragments, or are reabsorbed in a process known as <OpenstaxTerm>reuptake</OpenstaxTerm>. Reuptake involves the neurotransmitter being pumped back into the neuron that released it, in order to clear the synapse (<a href="#CNX_Psych_03_02_Reuptake">Figure 3.12</a>). Clearing the synapse serves both to provide a clear “on” and “off” state between signals and to regulate the production of neurotransmitter (full synaptic vesicles provide signals that no additional neurotransmitters need to be produced).
</OpenstaxParagraph>
<OpenstaxFigure id="CNX_Psych_03_02_Reuptake" src="https://openstax.org/apps/archive/20240226.174525/resources/5702a778859ad92103597c3eae5b473b388b3791" alt="The synaptic space between two neurons is shown. Some neurotransmitters that have been released into the synapse are attaching to receptors while others undergo reuptake into the axon terminal." mediaType="image/jpeg" width="649" height="418" />
<OpenstaxFigureText width="649">
	Figure 3.12 Reuptake involves moving a neurotransmitter from the synapse back into the axon terminal from which it was released.
</OpenstaxFigureText>
<OpenstaxParagraph>
	Neuronal communication is often referred to as an electrochemical event. The movement of the action potential down the length of the axon is an electrical event, and movement of the neurotransmitter across the synaptic space represents the chemical portion of the process. However, there are some specialized connections between neurons that are entirely electrical. In such cases, the neurons are said to communicate via an electrical synapse. In these cases, two neurons physically connect to one another via gap junctions, which allows the current from one cell to pass into the next. There are far fewer electrical synapses in the brain, but those that do exist are much faster than the chemical synapses that have been described above (Connors &amp; Long, 2004).
</OpenstaxParagraph>
<OpenstaxNote>
	<OpenstaxNoteTitle> Link to Learning </OpenstaxNoteTitle> 
	<OpenstaxParagraph>
		Watch this <a href="http://openstax.org/l/neuroncom">video about neuronal communication</a> to learn more.
	</OpenstaxParagraph>
</OpenstaxNote>

3.2.2 Neuronal Communication

1 Introduction to Psychology

1.1 What Is Psychology?

1.1.1 Why Study Psychology?

1.2 History of Psychology

1.2.1 Wundt and Structuralism

1.2.2 Functionalism

1.2.3 Freud and Psychoanalytic Theory

1.2.4 Wertheimer, Koffka, Köhler, and Gestalt Psychology

1.2.5 Pavlov, Watson, Skinner, and Behaviorism

1.2.6 Maslow, Rogers, and Humanism

1.2.7 The Cognitive Revolution

1.2.8 Multicultural And Cross-Cultural Psychology

1.2.9 Women in Psychology

1.3 Contemporary Psychology

1.3.1 Biopsychology and Evolutionary Psychology

1.3.2 Sensation and Perception

1.3.3 Cognitive Psychology

1.3.4 Developmental Psychology

1.3.5 Personality Psychology

1.3.6 Social Psychology

1.3.7 Industrial-Organizational Psychology

1.3.8 Health Psychology

1.3.9 Sport and Exercise Psychology

1.3.10 Clinical Psychology

1.3.11 Forensic Psychology

1.4 Careers in Psychology

1.4.1 Other Careers in Academic Settings

1.4.2 Career Options Outside of Academic Settings

2 Psychological Research

2.1 Why Is Research Important?

2.1.1 Use of Research Information

2.1.2 NOTABLE RESEARCHERS

2.1.3 The Process of Scientific Research

2.2 Approaches to Research

2.2.1 Clinical or Case Studies

2.2.2 Naturalistic Observation

2.2.3 Surveys

2.2.4 Archival Research

2.2.5 Longitudinal and Cross-Sectional Research

2.3 Analyzing Findings

2.3.1 Correlational Research

2.3.2 Causality: Conducting Experiments and Using the Data

2.3.3 Reliability and Validity

2.4 Ethics

2.4.1 Research Involving Human Participants

2.4.2 Research Involving Animal Subjects

3 Biopsychology

3.1 Human Genetics

3.1.1 Genetic Variation

3.1.2 Gene-Environment Interactions

3.2 Cells of the Nervous System

3.2.1 Neuron Structure

3.2.3 Neurotransmitters and Drugs

3.3 Parts of the Nervous System

3.3.1 Peripheral Nervous System

3.4 The Brain and Spinal Cord

3.4.1 The Spinal Cord

3.4.2 The Two Hemispheres

3.4.3 Forebrain Structures

3.4.4 Midbrain and Hindbrain Structures

3.4.5 Brain Imaging

3.5 The Endocrine System

3.5.1 Major Glands

4 States of Consciousness

4.1 What Is Consciousness?

4.1.1 Biological Rhythms

4.1.2 Problems With Circadian Rhythms

4.2 Sleep and Why We Sleep

4.2.1 What is Sleep?

4.2.2 Why Do We Sleep?

4.3 Stages of Sleep

4.3.1 NREM Stages of Sleep

4.3.2 REM Sleep

4.4 Sleep Problems and Disorders

4.4.1 Insomnia

4.4.2 Parasomnias

4.4.3 Sleep Apnea

4.4.4 Narcolepsy

4.5 Substance Use and Abuse

4.5.1 Substance Use Disorders

4.5.2 Drug Categories

4.6 Other States of Consciousness

4.6.1 Hypnosis

4.6.2 Meditation

5 Sensation and Perception

5.1 Sensation versus Perception

5.1.1 Sensation

5.1.2 Perception

5.2 Waves and Wavelengths

5.2.1 Amplitude and Wavelength

5.2.2 Light Waves

5.2.3 Sound Waves

5.3 Vision

5.3.1 Anatomy of the Visual System

5.3.2 Color and Depth Perception

5.4 Hearing

5.4.1 Anatomy of the Auditory System

5.4.2 Pitch Perception

5.4.3 Sound Localization

Question	Answer
electrical signal that moves down the neuron’s axon	action potential
phenomenon that incoming signal from another neuron is either sufficient or insufficient to reach the threshold of excitation	all-or-none
difference in charge across the neuronal membrane	membrane potential
cells in the nervous system that act as interconnected information processors, which are essential for all of the tasks of the nervous system	neuron
the state of readiness of a neuron membrane’s potential between signals	resting potential
neurotransmitter is pumped back into the neuron that released it	reuptake
level of charge in the membrane that causes the neuron to become active	threshold of excitation