Learn Hardcore Spanish (Latin America): Me siento bien informado después de leer el informe. - I feel well informed after reading the report.

Me siento is the first-person singular present of the reflexive verb sentirse, meaning “I feel” (as in “I feel a certain way”). The me is a reflexive pronoun required by sentirse to indicate that the feeling refers back to the subject (myself).

Why is bien informado used instead of informado bien?

In Spanish, the adverb bien typically precedes the adjective or past participle it modifies. So you say bien informado (“well informed”) rather than informado bien, which sounds unnatural.

What is the difference between informado and informativo?

Informado is the past participle of informar, used as an adjective to mean “informed” (having received information).
Informativo is an adjective meaning “informative” (providing or intended to provide information).

Why is it el informe and not la informe?

In Spanish, informe is a masculine noun (even though it ends in -e, which doesn’t always signal gender). Masculine nouns take el as the singular definite article.

Why do we say después de leer instead of a conjugated verb?

Después de is a preposition meaning “after.” When a preposition connects to another verb, that verb must remain in the infinitive form—hence leer (“to read”), not leí or lees.

Can I replace después de leer el informe with al leer el informe?

Yes. Al leer means “upon reading” or “when reading.” So
Me siento bien informado al leer el informe
is also correct and emphasizes that the feeling occurs as you read.

If a female speaker says this, should it be informada instead of informado?

Exactly. When a past participle functions as an adjective, it must agree in gender (and number) with the noun it describes. A woman would say:
Me siento bien informada después de leer el informe.

How can I say “I feel very well informed” in Spanish?

Just add muy before bien:
Me siento muy bien informado
(or muy bien informada for a female speaker).