Što se tiče završnog ispita, predavač će objasniti gradivo.

Što se tiče is a very common fixed expression meaning:

• as for
• regarding
• when it comes to
• as far as ... is concerned

So Što se tiče završnog ispita... means As for the final exam... or Regarding the final exam...

It is best learned as a whole phrase, because its literal structure is not very helpful to an English speaker. In normal usage, it introduces a topic and then says something about that topic.

Examples:

• Što se tiče posla, sve je u redu. = As for work, everything is fine.
• Što se tiče Marka, ne znam ništa. = As for Marko, I don’t know anything.

Because što se tiče is followed by the genitive case.

The base form is:

• završni ispit = final exam

After što se tiče, both words change to genitive singular:

• završnog ispita

So:

• što se tiče završnog ispita = regarding the final exam

This is a pattern you should memorize:

• što se tiče + genitive

More examples:

• što se tiče vremena = regarding the weather
• što se tiče škole = regarding school
• što se tiče profesora = regarding the professor

Because the adjective must agree with the noun it describes in:

• gender
• number
• case

Here:

• ispit is masculine singular
• after što se tiče, it must be in the genitive singular
• so the adjective završni also becomes genitive singular masculine

That gives:

• završni ispit → završnog ispita

This kind of agreement happens all the time in Serbian.

Predavač means something like:

• lecturer
• instructor
• sometimes more generally the person giving the lecture/class

It is not always exactly the same as:

• profesor = professor / teacher
• nastavnik = teacher
• učitelj = primary-school teacher

So in this sentence, predavač suggests someone who is presenting or teaching the material, especially in a more academic or course-based setting.

This is the standard way to form the future tense in Serbian:

• a form of hteti in its short/clitic form
• plus the infinitive

Here:

• će = will
• objasniti = to explain

So:

• predavač će objasniti = the lecturer will explain

Other examples:

• Ja ću doći. = I will come.
• Oni će učiti. = They will study.

In standard Serbian, the future can often appear in two closely related forms:

• predavač će objasniti gradivo
• predavač objasniće gradivo

However, the first version, će + infinitive, is usually the clearest and most neutral for learners.

You may also see the future written as one word in some cases, especially when the infinitive loses its final -i:

• objasniće

But predavač će objasniti gradivo is completely standard and very natural.

Objasniti means to explain and is the perfective form of the verb.

In Serbian, many verbs come in aspect pairs:

• objašnjavati = imperfective, ongoing/repeated explaining
• objasniti = perfective, explain successfully / explain as a completed act

Here the sentence refers to one future completed action:

• the lecturer will explain the material

So objasniti fits very well.

A rough contrast:

• Predavač će objašnjavati gradivo. = The lecturer will be explaining the material / will spend time explaining it.
• Predavač će objasniti gradivo. = The lecturer will explain the material.

Gradivo means:

• material
• subject matter
• course content
• what has to be studied/covered

It is a very common school and university word in Serbian.

So objasniti gradivo means:

• explain the material
• go over the course content

It does not usually mean physical material. It refers to academic content.

Examples:

• Moram da učim gradivo za ispit. = I have to study the material for the exam.
• Gradivo je teško. = The material is difficult.

Because Serbian has no articles like a, an, or the.

So nouns appear without articles, and definiteness is understood from context.

For example:

• završni ispit can mean a final exam or the final exam
• gradivo can mean material or the material

In this sentence, context makes it clear that English would naturally use the:

• the final exam
• the material

The short form će is a clitic, and clitics in Serbian usually appear in the second position of the clause.

So:

• Predavač će objasniti gradivo.

Here, predavač is in first position, and će comes right after it.

This is very typical Serbian word order.

You can sometimes change word order for emphasis, but clitics still tend to stay near the beginning:

• Gradivo će predavač objasniti kasnije.
  = The material, the lecturer will explain later.

For learners, it is safest to remember:

• put the main topic or subject first
• put će right after that first element

In this fixed expression, što se tiče is the normal and standard form.

Even speakers who often use šta in other contexts usually say:

• što se tiče...

So it is best to memorize the phrase exactly like this:

• što se tiče + genitive

Yes, the comma is natural and normally expected here.

The opening phrase:

• Što se tiče završnog ispita

functions like a topic-setting expression: As for the final exam...

In English, we also often separate that kind of phrase with a comma:

• As for the final exam, the lecturer will explain the material.

So the Serbian punctuation matches the structure well.