tā de qīzi zài yínháng.

的 marks possession or a close relationship, similar to 's or of in English.

So:

• 他 = he / him
• 他的 = his
• 妻子 = wife

So 他的妻子 means his wife.

A very common Mandarin pattern is:

possessor + 的 + noun

Examples:

• 我的朋友 = my friend
• 她的老师 = her teacher
• 他的妻子 = his wife

Sometimes yes in natural Mandarin, especially with family members and close personal relationships, but it depends on the word and style.

For example, people often say:

• 我妈妈 = my mom
• 他爸爸 = his dad

With 妻子, keeping 的 is very normal and sounds clear and standard:

• 他的妻子

If you omit it and say 他妻子, it can sound more compressed, more literary, or less natural for many learners' everyday speech. So as a learner, 他的妻子 is the safest choice.

Here 在 means to be at / to be in / to be located at.

So:

• 他的妻子在银行。 = His wife is at the bank.

In this sentence, 在 is functioning as the main verb, so you do not need 是.

A very common Mandarin pattern is:

noun + 在 + place

Examples:

• 我在家。 = I am at home.
• 她在学校。 = She is at school.
• 书在桌子上。 = The book is on the table.

Because 是 is usually used to connect one noun to another noun:

• 他是老师。 = He is a teacher.

But for location, Mandarin usually uses 在, not 是:

• 他在银行。 = He is at the bank.
• not normally 他是银行 for location

So in your sentence, 在 is the correct word because the sentence is about where his wife is.

By itself, it most naturally means:

• His wife is at the bank
• or His wife is in the bank

It tells you her location, not necessarily her job.

If you want to say she works there, Mandarin would usually say something more explicit, such as:

• 他的妻子在银行工作。 = His wife works at the bank.
• 他的妻子是银行职员。 = His wife is a bank employee.

So without 工作 or another job-related phrase, the sentence is mainly about location.

Mandarin does not use articles like a, an, and the in the same way English does.

So:

• 妻子 can mean wife / a wife / the wife, depending on context
• 银行 can mean bank / a bank / the bank, depending on context

In this sentence, context tells us the natural English translation is his wife is at the bank.

This is very normal in Mandarin. You often do not need an article at all.

妻子 is pronounced qīzi.

Important details:

• 妻 = qī with the first tone
• 子 here is usually pronounced with a neutral tone, so it sounds light: zi

So it is not usually said as qīzǐ in normal speech. It is more like:

• qīzi

This neutral-tone pattern is very common in Mandarin, especially in the second syllable of many everyday words.

Because 行 is a character with more than one pronunciation.

Common readings include:

• xíng = okay; to go; capable
• háng = line; row; profession; certain set expressions

In 银行 (bank), the correct pronunciation is:

• yínháng

So even though you may know 行 as xíng, in this word it must be háng.

This is very common in Mandarin: one character can have different pronunciations in different words.

Yes, but it has a somewhat neutral or formal feel.

Common words for wife include:

• 妻子 = wife; fairly standard, somewhat formal/written
• 太太 = wife / Mrs.; polite, common in some contexts
• 老婆 = wife; very common in everyday speech, more colloquial
• 爱人 = spouse; used in some regions or styles

So 他的妻子 is perfectly correct and natural, especially in standard written Chinese or careful speech.

If you were speaking casually, you might also hear:

• 他老婆在银行。

The structure is:

他 的 妻子 在 银行。
possessor + 的 + noun + 在 + place

More generally:

[person/thing] + 在 + [location]

So the sentence breaks down as:

• 他 = he
• 的 = possessive marker
• 妻子 = wife
• 在 = is at / is in
• 银行 = bank

This word order is very common and useful for making simple location sentences in Mandarin.

Yes, 他 by itself means he, but when you add 的, it becomes possessive:

• 他 = he
• 他的 = his

This works with other pronouns too:

• 我 = I / me → 我的 = my / mine
• 你 = you → 你的 = your / yours
• 她 = she / her → 她的 = her / hers

So 他的妻子 literally follows the same pattern as his wife.

No. In standard Mandarin, 他 and 她 are both pronounced tā.

So:

• 他 = he
• 她 = she

They sound the same when spoken. The difference is visible only in writing.

This means that if you hear tā de qīzi, you need context to know whether the speaker means his wife or, in another sentence pattern, a different written pronoun. In your sentence, the written character 他 tells you it is his.