Questions & Answers about Эта книга самая интересная.
There are two common ways:
• One-word form: интереснее (e.g. Эта книга интереснее той – “This book is more interesting than that one.”)
• Two-word form with более: более интересная (e.g. более интересная книга – “a more interesting book”).
You use the interrogative какая (feminine nominative) and the same superlative construction:
Какая книга самая интересная?
• Самая интересная книга is a noun phrase meaning “the most interesting book,” used when you’re naming or listing it.
• Эта книга самая интересная is a full sentence stating that “this book is the most interesting (of all),” often in response to a question or in comparison.
Nominative case forms of самый:
• Masculine singular: самый
• Feminine singular: самая
• Neuter singular: самое
• Plural (all genders): самые