मांसपेशी में दर्द है; धीरे साँस लीजिए।

में is the postposition meaning in.

So मांसपेशी में दर्द है is literally something like there is pain in the muscle. Hindi often describes physical discomfort this way:

• सिर में दर्द है = there is pain in the head / my head hurts
• पीठ में दर्द है = there is pain in the back
• मांसपेशी में दर्द है = there is pain in the muscle

This is a very common pattern in Hindi for talking about pain.

Hindi often expresses pain as pain exists/is present rather than using a direct equivalent of English hurt.

So the structure is:

• [body part] + में + दर्द + है

Literally: There is pain in [body part].

This is one of the most natural ways to talk about aches and pains in Hindi. English prefers My muscle hurts, but Hindi often prefers There is pain in the muscle.

मांसपेशी means muscle and it is usually treated as a feminine noun.

In this sentence, it is singular: the muscle or a muscle.

A few useful forms:

• मांसपेशी = muscle
• मांसपेशियाँ = muscles

Because it ends in -ी, it does not visibly change before में:

• मांसपेशी में = in the muscle

Hindi often leaves out possessives like my when the meaning is obvious from context, especially with body parts, symptoms, and medical instructions.

So instead of saying:

• मेरी मांसपेशी में दर्द है

Hindi may simply say:

• मांसपेशी में दर्द है

The listener usually understands whose body is being discussed from the situation.

That said, मेरी मांसपेशी में दर्द है is also possible if you want to make it explicit.

धीरे here means slowly or gently. It is functioning as an adverb, modifying the action of breathing.

So:

• धीरे साँस लीजिए = breathe slowly / take a slow breath

Because it is being used adverbially, it does not change for gender or number here.

A related point: learners often connect धीरे with slow, but in Hindi the adjective you often learn is धीमा:

• धीमा = slow
• धीरे = slowly

Literally, साँस लीजिए means take breath.

Hindi commonly uses the expression:

• साँस लेना = to breathe / to take a breath

So लीजिए comes from लेना (to take), and the whole phrase means:

• साँस लीजिए = breathe / take a breath

This is very natural Hindi. Even though English usually just says breathe, Hindi often uses the noun + verb combination साँस लेना.

लीजिए is a polite imperative form. It is used when speaking respectfully, gently, or professionally.

That makes it very suitable for medical, caregiving, or instructional situations.

Compare:

• ले / लो = informal
• लीजिए = polite / respectful

So धीरे साँस लीजिए sounds appropriate for addressing a patient, elder, stranger, or anyone you want to address politely.

Yes, absolutely. धीरे-धीरे साँस लीजिए is very natural and often sounds even more like spoken instruction.

The difference is subtle:

• धीरे साँस लीजिए = breathe slowly
• धीरे-धीरे साँस लीजिए = breathe slowly, gradually, gently

In real speech, both are common.

साँस is pronounced roughly like saans.

The sign ँ shows nasalization. It gives the vowel a nasal sound, so it is not a plain सास.

A rough pronunciation guide:

• सा = saa
• साँ = nasalized saa
• साँस = saans

For an English speaker, saying saans is a good approximation.

Yes. That is also natural Hindi.

Compare:

• मांसपेशी में दर्द है = there is pain in the muscle
• मांसपेशी में दर्द हो रहा है = the muscle is hurting / pain is happening in the muscle

The version with है sounds like a simple statement of condition.
The version with हो रहा है can sound a bit more immediate or ongoing.

Both are correct; the sentence you were given is just a shorter, very common way to say it.

The semicolon is just punctuation joining two closely related parts:

• statement of the problem: मांसपेशी में दर्द है
• instruction: धीरे साँस लीजिए

In everyday Hindi writing, you might also see a comma, a full stop, or even just a pause in speech. The meaning does not really change.

The given order is the most natural one.

Hindi often places adverbs like धीरे before the verb phrase:

• धीरे साँस लीजिए

If you move the words around too much, it can sound awkward or overly marked. So for a learner, this is the best order to remember.

A good pattern is:

• [adverb] + [noun/object] + [verb]

Here:

• धीरे
  • साँस
    • लीजिए