Die Teamleiterin leitet das Seminar.

The team leader leads the seminar.

Breakdown of Die Teamleiterin leitet das Seminar.

• das Seminar: the seminar
• die Teamleiterin: the team leader (female)
• leiten: to lead

Questions & Answers about Die Teamleiterin leitet das Seminar.

Why does Teamleiterin end in -in? What does that tell me?

The ending -in is the regular marker for a female person in many German job titles and roles.

• Teamleiter = team leader (male, or grammatically masculine / generic)
• Teamleiterin = female team leader

So Teamleiterin tells you the team leader is a woman.
Grammar-wise, Teamleiterin is a feminine noun, which affects the article (die, eine, etc.) and adjective endings.

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Why is it die Teamleiterin and not der Teamleiterin or das Teamleiterin?

Because Teamleiterin is grammatically feminine, and in the nominative singular (the subject form), the definite article for feminine nouns is die.

Very short overview for singular nouns:

• der = masculine nominative (e.g. der Lehrer)
• die = feminine nominative (e.g. die Lehrerin)
• das = neuter nominative (e.g. das Kind)

So as the subject, Teamleiterin must take die:
Die Teamleiterin leitet …

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What case are die Teamleiterin and das Seminar in?