آخر هفته همه میخواهند کمی استراحت کنند.

Yes, literally آخر هفته means the end of the week:

• آخر = end / last
• هفته = week

In Persian, this expression is commonly used to mean the weekend. So even though the literal meaning is end of the week, the natural English translation is usually weekend.

Persian often puts time expressions near the beginning of the sentence. So:

• آخر هفته = at the weekend / on the weekend
• همه = everyone
• می‌خواهند = want
• کمی استراحت کنند = to rest a little

A very literal word order would be:

At the weekend, everyone wants to rest a little.

This is normal Persian word order.

همه can mean everyone, everybody, or all, depending on context.

In this sentence, because it refers to people in general, it means:

• everyone
• everybody

So همه می‌خواهند = everyone wants / everybody wants

That is a very common question.

In English, everyone is grammatically singular, so you say:

• Everyone wants

In Persian, همه often takes a plural verb when it refers to multiple people:

• همه می‌خواهند = everyone wants

So even though English uses singular grammar, Persian often treats همه as a group of multiple people and uses a plural verb.

Yes. In standard modern Persian spelling, the preferred form is:

• می‌خواهند

with a half-space (called a zero-width non-joiner) between می and خواهند.

So the most standard written version of the sentence is:

آخر هفته همه می‌خواهند کمی استراحت کنند.

You may still see میخواهند written without the half-space, especially in informal typing, but می‌خواهند is the standard spelling.

می‌خواهند is the present tense of خواستن (to want) for they.

Breakdown:

• می‌- = present/imperfective marker
• خواه = present stem of خواستن
• -ند = they

So می‌خواهند literally means:

• they want

Because همه refers to multiple people, the verb is plural.

In everyday speech, this is often pronounced more like می‌خوان.

Because Persian often expresses want to do something using:

خواستن + subjunctive verb

So:

• می‌خواهند = they want
• استراحت کنند = that they rest / to rest

Together:

• می‌خواهند ... کنند = they want to do ...

This is different from English, which uses to + infinitive:

• everyone wants to rest

Persian does not use an English-style infinitive here.

Because after خواستن (to want), Persian usually uses the subjunctive form, not the dictionary form.

The dictionary form is:

• استراحت کردن = to rest

But after می‌خواهند, you need:

• استراحت کنند = (that) they rest / to rest

Here کنند is the subjunctive/plural form of کردن.

So:

• می‌خواهند استراحت کنند = they want to rest

not:

• می‌خواهند استراحت کردن ❌

استراحت کردن is a very common compound verb in Persian.

• استراحت = rest
• کردن = to do

But together, استراحت کردن means:

• to rest

Many Persian verbs work this way: a noun or verbal element + کردن.

So in this sentence:

• استراحت کنند = (they) rest

Even though it looks literally like do rest, it should be understood as the normal Persian verb meaning to rest.

کمی means:

• a little
• a bit
• somewhat

So کمی استراحت کنند means:

• rest a little
• get a little rest

It softens the idea and makes it sound natural: not a huge amount of rest, just a bit of rest.

In Persian, words like کمی often come before the noun or verbal phrase they modify.

So:

• کمی استراحت کنند = rest a little / get a little rest

This placement is natural in Persian. English often puts a little after the verb or before a noun, but Persian commonly places کمی before the element it modifies.

The sentence follows a typical Persian pattern:

Time + subject + verb/complement

More specifically:

• آخر هفته = time expression
• همه = subject
• می‌خواهند = main verb
• کمی استراحت کنند = complement

A very literal arrangement would be:

At the weekend everyone wants a little rest to do.

That sounds strange in English, but it reflects Persian’s subject-object-verb tendencies and its use of compound verbs.

In colloquial Persian, this sentence is often pronounced more like:

آخر هفته همه می‌خوان کمی استراحت کنن.

Compared with the formal written version:

• می‌خواهند → می‌خوان
• کنند → کنن

So:

• written/formal: آخر هفته همه می‌خواهند کمی استراحت کنند.
• spoken/colloquial: آخر هفته همه می‌خوان کمی استراحت کنن.

Both mean the same thing.

The version you were given is standard written Persian, so it is fairly neutral to formal.

• می‌خواهند
• کنند

are standard written forms.

In ordinary conversation, many speakers would use more colloquial forms:

• می‌خوان
• کنن

So the sentence as written is perfectly correct, but a bit more written-style than everyday speech.